Recombinant Human LFNG cell lysate

• Cat.No.: LFNG-983HCL

Specification

• Species: Human
• Tag: Non
• Description: This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [ Homo sapiens ]
• Official Symbol: LFNG
• Synonyms: LFNG; LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; lunatic fringe (Drosophila) homolog , lunatic fringe homolog (Drosophila); beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; SCDO3
• Gene ID: 3955
• mRNA Refseq: NM_001040167
• Protein Refseq: NP_001035257
• MIM: 602576
• UniProt ID: Q8NES3
• Chromosome Location: 7p22.3
• Pathway: Delta-Notch Signaling Pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, conserved biosystem; Other types of O-glycan biosynthesis, organism-specific biosystem; Other types of O-glycan biosynthesis, conserved biosystem; Pre-NOTCH Expression and Processing, organism-specific biosystem; Pre-NOTCH Processing in Golgi, organism-specific biosystem
• Function: O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity; molecular_function; transferase activity, transferring glycosyl groups