Recombinant Human LDHB Protein, MYC/DDK-tagged

• Cat.No.: LDHB-424H
• Product Overview: Recombinant human LDHB protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 36.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: lactate dehydrogenase B [ Homo sapiens ]
• Official Symbol: LDHB
• Synonyms: HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5
• Gene ID: 3945
• mRNA Refseq: NM_001174097.1
• Protein Refseq: NP_001167568.1
• MIM: 150100
• UniProt ID: P07195