Recombinant Human LAT2, His-tagged

• Cat.No.: LAT2-29925TH
• Product Overview: Recombinant fragment, corresponding to amino acids 27-243 of Human NTAL with N terminal His tag; 238 amino acids with tag, MWt 26.2kDa.

Specification

• Description: This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein.
• Protein length: 217 amino acids
• Conjugation: HIS
• Molecular Weight: 26.200kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. Also expressed in placenta, lung, pancreas and small intestine. Present in B-cells, NK cells and monocytes. Absent from T-cells (at protein level).
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MRCSRPGAKR SEKIYQQRSL REDQQSFTGS RTYSLVGQAW PGPLADMAPT RKDKLLQFYP SLEDPASSRY QNFSKGSRHG SEEAYIDPIA MEYYNWGRFS KPPEDDDANS YENVLICKQK TTETGAQQEG IGGLCRGDLS LSLALKTGPT SGLCPSASPE EDEESEDYQN SASIHQWRES RKVMGQLQRE ASPGPVGSPD EEDGEPDYVN GEVAATEA

Gene Information

• Gene Name: LAT2 linker for activation of T cells family, member 2 [ Homo sapiens ]
• Official Symbol: LAT2
• Synonyms: LAT2; linker for activation of T cells family, member 2; WBSCR5, WBSCR15, Williams Beuren syndrome chromosome region 5; linker for activation of T-cells family member 2; HSPC046; LAB; linker for activation of B cells; linker for activation of T cells; tr
• Gene ID: 7462
• mRNA Refseq: NM_014146
• Protein Refseq: NP_054865
• MIM: 605719
• Uniprot ID: Q9GZY6
• Chromosome Location: 7q11.23
• Pathway: B Cell Receptor Signaling Pathway, organism-specific biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem
• Function: SH2 domain binding; protein binding