Recombinant Human KRT81 cell lysate

• Cat.No.: KRT81-958HCL

Specification

• Description: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot
• Tag: Non

Gene Information

• Gene Name: KRT81 keratin 81 [ Homo sapiens ]
• Official Symbol: KRT81
• Synonyms: KRT81; keratin 81; keratin, hair, basic, 1 , KRTHB1; keratin, type II cuticular Hb1; hard keratin type II 1; Hb 1; K81; ghHb1; MLN 137; keratin-81; hair keratin K2.9; type-II keratin Kb21; keratin, hair, basic, 1; hard keratin, type II, 1; type II hair keratin Hb1; metastatic lymph node 137 gene protein; HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1
• Gene ID: 3887
• mRNA Refseq: NM_002281
• Protein Refseq: NP_002272
• MIM: 602153
• UniProt ID: Q14533
• Chromosome Location: 12q13
• Function: protein binding; structural molecule activity