Recombinant Human KPNA5

• Cat.No.: KPNA5-29811TH
• Product Overview: Recombinant full length Human KPNA5 with N terminal proprietary tag, Predicted MWt 85.4 kDa including the tag.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: Non
• Protein Length: 539 amino acids
• Description: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus.
• Molecular Weight: 85.400kDa inclusive of tags
• Tissue specificity: Testis.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MDAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRK QKREEQLFKRRNVYLPRNDESMLESPIQDPDISSTVPIPE EEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPID QVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTF LHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGD NAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNL CRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALS YLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRA VGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEAC WTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKE AAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKI VQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLD KIEFLQSHENQEIYQKAFDLIEHYFGVEEDDPSIVPQVDE NQQQFIFQQQEAPMDGFQL
• Sequence Similarities: Belongs to the importin alpha family.Contains 10 ARM repeats.Contains 1 IBB domain.

Gene Information

• Gene Name: KPNA5 karyopherin alpha 5 (importin alpha 6) [ Homo sapiens ]
• Official Symbol: KPNA5
• Synonyms: KPNA5; karyopherin alpha 5 (importin alpha 6); importin subunit alpha-6; IPOA6; SRP6
• Gene ID: 3841
• mRNA Refseq: NM_002269
• Protein Refseq: NP_002260
• MIM: 604545
• Uniprot ID: O15131
• Chromosome Location: 6q22.2
• Function: binding; protein binding; protein transporter activity