Recombinant Human KLK4 Protein, His-tagged

• Cat.No.: KLK4-685H
• Product Overview: Recombinant Human KLK4(Ser27~Ser254) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Ser27~Ser254
• Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Several transcript variants encoding different proteins have been found for this gene.
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 28.1kDa
• Identity: Reconstitute in PBS or others
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: KLK4 kallikrein-related peptidase 4 [ Homo sapiens ]
• Official Symbol: KLK4
• Synonyms: KLK4; kallikrein-related peptidase 4; kallikrein 4 (prostase, enamel matrix, prostate) , PRSS17; kallikrein-4; EMSP; EMSP1; KLK L1; PSTS; prostase; serine protease 17; kallikrein-like protein 1; androgen-regulated message 1; enamel matrix serine protease 1; enamel matrix serine proteinase 1; ARM1; AI2A1; KLK-L1; PRSS17; kallikrein; MGC116827; MGC116828
• Gene ID: 9622
• mRNA Refseq: NM_004917
• Protein Refseq: NP_004908
• MIM: 603767
• UniProt ID: Q9Y5K2