Recombinant Human Killer Cell Lectin-Like Receptor Subfamily C, Member 3, His-tagged

• Cat.No.: KLRC3-7170H
• Product Overview: Recombinant human KLRC3 protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 19 kDa.

Specification

• Description: KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M NaCl, 10% glycerol.
• Molecular Mass: 19 kDa (171aa)
• Protein length: 94-240aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMIPFLEQ NNSSPNTRTQ KARPCGHCPE EWITYSNSCY YIGKERRTWE ESLQACASKN SSSLLSIDNE EEMKFLASIL PSSWIGVFRN SSHHPWVTIN GLAFKHEIKD SDHAERNCAM LHVRGLISDQ CGSSRIIRRG FIMLTRLVLN S
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: KLRC3 killer cell lectin-like receptor subfamily C, member 3 [ Homo sapiens ]
• Official Symbol: KLRC3
• Synonyms: KLRC3; killer cell lectin-like receptor subfamily C, member 3; NKG2-E type II integral membrane protein; NKG2 E; NK cell receptor E; NKG2-E-activating NK receptor; NKG2E; NKG2-E
• Gene ID: 3823
• mRNA Refseq: NM_002261
• Protein Refseq: NP_002252
• MIM: 602892
• UniProt ID: Q07444
• Chromosome Location: 12p13
• Pathway: Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Natural killer cell mediated cytotoxicity, organism-specific biosystem; Natural killer cell mediated cytotoxicity, conserved biosystem
• Function: binding; receptor activity; sugar binding; transmembrane signaling receptor activity