Recombinant Human KDM4A Protein (M1-L359), Tag Free
Cat.No. : | KDM4A-0531H |
Product Overview : | Recombinant Human JMJD2A(M1-L359) Protein was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Protein Length : | M1-L359 |
Description : | Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. |
Form : | Liquid |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name | KDM4A lysine (K)-specific demethylase 4A [ Homo sapiens (human) ] |
Official Symbol | KDM4A |
Synonyms | KDM4A; lysine (K)-specific demethylase 4A; JMJD2, JMJD2A, jumonji domain containing 2, jumonji domain containing 2A; lysine-specific demethylase 4A; JHDM3A; jumonji C domain containing histone demethylase 3A; KIAA0677; jumonji domain containing 2; jumonji domain containing 2A; jumonji domain-containing protein 2A; jumonji C domain-containing histone demethylase 3A; jmjC domain-containing histone demethylation protein 3A; JMJD2; JMJD2A; |
Gene ID | 9682 |
mRNA Refseq | NM_014663 |
Protein Refseq | NP_055478 |
MIM | 609764 |
UniProt ID | O75164 |
◆ Recombinant Proteins | ||
KDM4A-8591M | Recombinant Mouse KDM4A Protein | +Inquiry |
KDM4A-094H | Recombinant Human KDM4A Protein, His-tagged | +Inquiry |
KDM4A-50H | Active Recombinant Human KDM4A, FLAG-tagged | +Inquiry |
KDM4A-69H | Recombinant Human KDM4A Protein, StepII-tagged | +Inquiry |
KDM4A-0532H | Recombinant Human KDM4A Protein (M1-L359), His tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
KDM4A-4996HCL | Recombinant Human KDM4A 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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