Recombinant Human KCNJ12, GST-tagged

• Cat.No.: KCNJ12-252H
• Product Overview: Recombinant Human KCNJ12 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 182-433aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: KCNJ12 potassium inwardly-rectifying channel, subfamily J, member 12 [ Homo sapiens ]
• Official Symbol: KCNJ12
• Synonyms: KCNJ12; potassium inwardly-rectifying channel, subfamily J, member 12; KCNJN1, potassium inwardly rectifying channel, subfamily J, inhibitor 1; ATP-sensitive inward rectifier potassium channel 12; hIRK1; IRK2; Kir2.2; Kir2.2v; inward rectifier K(+) channel Kir2.2; inward rectifier K(+) channel Kir2.6; inward rectifier K(+) channel Kir2.2v; potassium channel, inwardly rectifying subfamily J member 12; potassium inwardly-rectifying channel, subfamily J, inhibitor 1; hIRK; IRK-2; KCNJN1; kcnj12x; hkir2.2x; FLJ14167
• Gene ID: 3768
• mRNA Refseq: NM_021012
• Protein Refseq: NP_066292
• MIM: 602323
• UniProt ID: Q14500
• Chromosome Location: 17p11.1
• Pathway: Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Cholinergic synapse, organism-specific biosystem; Classical Kir channels, organism-specific biosystem; G protein gated Potassium channels, organism-specific biosystem; GABA B receptor activation, organism-specific biosystem; GABA receptor activation, organism-specific biosystem
• Function: PDZ domain binding; inward rectifier potassium channel activity; ion channel inhibitor activity; potassium channel regulator activity; voltage-gated ion channel activity