Recombinant Human Kallikrein-Related Peptidase 7, His-tagged

Cat.No. : KLK7-7169H
Product Overview : Recombinant human KLK7 protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 27.1 kDa.
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Species : Human
Source : E.coli
Tag : His
Protein Length : 30-253aa
Description : KLK7 is a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikreins are biomarkers for cancer. The protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. KLK7 may play a role in cancer invasion and metastasis, and increased expression of this protein is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M UREA, 10% glycerol.
Molecular Mass : 27.1 kDa (249aa)
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSHMIIDGA PCARGSHPWQ VALLSGNQLH CGGVLVNERW VLTAAHCKMN EYTVHLGSDT LGDRRAQRIK ASKSFRHPGY STQTHVNDLM LVKLNSQARL SSMVKKVRLP SRCEPPGTTC TVSGWGTTTS PDVTFPSDLM CVDVKLISPQ DCTKVYKDLL ENSMLCAGIP DSKKNACNGD SGGPLVCRGT LQGLVSWGTF PCGQPNDPGV YTQVCKFTKW INDTMKKHR
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml (determined by Bradford assay)
Gene Name KLK7 kallikrein-related peptidase 7 [ Homo sapiens ]
Official Symbol KLK7
Synonyms KLK7; kallikrein-related peptidase 7; kallikrein 7 (chymotryptic, stratum corneum) , PRSS6; kallikrein-7; SCCE; signal protein; serine protease 6; stratum corneum chymotryptic enzyme; kallikrein 7 (chymotryptic, stratum corneum); hK7; PRSS6;
Gene ID 5650
mRNA Refseq NM_001243126
Protein Refseq NP_001230055
MIM 604438
UniProt ID P49862
Chromosome Location 19q13.33
Function peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity;

Not For Human Consumption!

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