Recombinant Human Kallikrein-Related Peptidase 7, His-tagged
Cat.No. : | KLK7-7169H |
Product Overview : | Recombinant human KLK7 protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 27.1 kDa. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 30-253aa |
Description : | KLK7 is a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikreins are biomarkers for cancer. The protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. KLK7 may play a role in cancer invasion and metastasis, and increased expression of this protein is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M UREA, 10% glycerol. |
Molecular Mass : | 27.1 kDa (249aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSHMIIDGA PCARGSHPWQ VALLSGNQLH CGGVLVNERW VLTAAHCKMN EYTVHLGSDT LGDRRAQRIK ASKSFRHPGY STQTHVNDLM LVKLNSQARL SSMVKKVRLP SRCEPPGTTC TVSGWGTTTS PDVTFPSDLM CVDVKLISPQ DCTKVYKDLL ENSMLCAGIP DSKKNACNGD SGGPLVCRGT LQGLVSWGTF PCGQPNDPGV YTQVCKFTKW INDTMKKHR |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name | KLK7 kallikrein-related peptidase 7 [ Homo sapiens ] |
Official Symbol | KLK7 |
Synonyms | KLK7; kallikrein-related peptidase 7; kallikrein 7 (chymotryptic, stratum corneum) , PRSS6; kallikrein-7; SCCE; signal protein; serine protease 6; stratum corneum chymotryptic enzyme; kallikrein 7 (chymotryptic, stratum corneum); hK7; PRSS6; |
Gene ID | 5650 |
mRNA Refseq | NM_001243126 |
Protein Refseq | NP_001230055 |
MIM | 604438 |
UniProt ID | P49862 |
Chromosome Location | 19q13.33 |
Function | peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity; |
◆ Recombinant Proteins | ||
KLK7-1959H | Recombinant Human KLK7 protein, His & GST-tagged | +Inquiry |
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KLK7-5019H | Recombinant Human KLK7 Protein (Glu23-Arg253), N-GST tagged | +Inquiry |
KLK7-4880M | Recombinant Mouse KLK7 Protein, His (Fc)-Avi-tagged | +Inquiry |
KLK7-564M | Active Recombinant Mouse KLK7 Protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
KLK7-1421MCL | Recombinant Mouse KLK7 cell lysate | +Inquiry |
KLK7-2428HCL | Recombinant Human KLK7 cell lysate | +Inquiry |
Not For Human Consumption!
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