Recombinant Human JPH1 protein, His & T7-tagged

• Cat.No.: JPH1-7875H
• Product Overview: Recombinant Human JPH1 aa. (Met1~Ala201 (Accession # Q9HDC5)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Met1~Ala201
• Description: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 25.3kDa.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 7.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: JPH1 junctophilin 1 [ Homo sapiens (human) ]
• Official Symbol: JPH1
• Synonyms: JPH1; junctophilin 1; JP1; JP-1; CMT2K; junctophilin-1; junctophilin type 1
• Gene ID: 56704
• mRNA Refseq: NM_001317830.1
• Protein Refseq: NP_001304759.1
• UniProt ID: Q9HDC5