Recombinant Human JMJD6 protein, His & T7-tagged

• Cat.No.: JMJD6-1968H
• Product Overview: Recombinant Human JMJD6 aa. (Met1~Glu334) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Met1~Glu334
• Description: This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 43.1kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 90%
• Characteristic: The isoelectric point is 9.3.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative
• Reconstitution: Reconstitute in sterile ddH2O.

Gene Information

• Gene Name: JMJD6 arginine demethylase and lysine hydroxylase [ Homo sapiens (human) ]
• Official Symbol: JMJD6
• Synonyms: CSAA; C-SAA
• Gene ID: 23210
• mRNA Refseq: NM_001081461.1
• Protein Refseq: NP_001074930.1
• UniProt ID: Q6NYC1