Recombinant Human JAK1 Protein, DYKDDDDK-tagged

• Cat.No.: JAK1-151H
• Product Overview: Recombinant Human Janus kinase 1(JAK1) protein, transcript variant 1(NM_002227), with a DYKDDDDK tag, was expressed in human cells.

Specification

• Species: Human
• Source: Human Cells
• Tag: Flag
• Description: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.38, without any preservatives.
• Molecular Mass: 133.1 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: JAK1 Janus kinase 1 [ Homo sapiens ]
• Official Symbol: JAK1
• Synonyms: JAK1; Janus kinase 1; JAK1B; tyrosine-protein kinase JAK1; JAK1A; JTK3
• Gene ID: 3716
• mRNA Refseq: NM_002227
• Protein Refseq: NP_002218
• MIM: 147795
• UniProt ID: P23458