Recombinant Human JAK1 protein, Flag-tagged, Biotinylated

• Cat.No.: JAK1-56H
• Product Overview: Recombinant Human JAK1, catalytic domain [850-1154(end) amino acids of accession number NP_002218.2] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Flag
• ProteinLength: 850-1154 a.a.
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 39 kDa
• Purity: >85% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: JAK1 Janus kinase 1 [ Homo sapiens ]
• Official Symbol: JAK1
• Synonyms: JAK1; Janus kinase 1; JAK1B; tyrosine-protein kinase JAK1; JAK1A; JTK3
• Gene ID: 3716
• mRNA Refseq: NM_002227
• Protein Refseq: NP_002218
• MIM: 147795
• UniProt ID: P23458
• Chromosome Location: 1p32.3-p31.3
• Pathway: Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem
• Function: ATP binding; growth hormone receptor binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein tyrosine kinase activity; protein tyrosine kinase activity