Recombinant Human JAG1 Protein, MYC/DDK-tagged

• Cat.No.: JAG1-792H
• Product Overview: Recombinant human JAG1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 133.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: jagged 1[ Homo sapiens ]
• Official Symbol: JAG1
• Synonyms: AGS; AHD; AWS; CD339; HJ1; JAGL1
• Gene ID: 182
• mRNA Refseq: NM_000214.2
• Protein Refseq: NP_000205
• UniProt ID: P78504