Recombinant Human IVD Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : IVD-5996H
Product Overview : IVD MS Standard C13 and N15-labeled recombinant protein (NP_002216) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Species : Human
Source : HEK293
Tag : Myc&DDK
Description : Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants have been found for this gene.
Molecular Mass : 46.2 kDa
AA Sequence : MATATRLLGCRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFHTRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name IVD isovaleryl-CoA dehydrogenase [ Homo sapiens (human) ]
Official Symbol IVD
Synonyms IVD; isovaleryl-CoA dehydrogenase; isovaleryl CoA dehydrogenase, isovaleryl Coenzyme A dehydrogenase; isovaleryl-CoA dehydrogenase, mitochondrial; ACAD2; isovaleryl CoA dehydrogenase; isovaleryl Coenzyme A dehydrogenase; FLJ12715; FLJ34849;
Gene ID 3712
mRNA Refseq NM_002225
Protein Refseq NP_002216
MIM 607036
UniProt ID P26440

Not For Human Consumption!

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