Recombinant Human ITGB8 cell lysate

• Cat.No.: ITGB8-881HCL

Specification

• Species: Human
• Tag: Non
• Description: This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: ITGB8 integrin, beta 8 [ Homo sapiens ]
• Official Symbol: ITGB8
• Synonyms: ITGB8; integrin, beta 8; integrin beta-8
• Gene ID: 3696
• mRNA Refseq: NM_002214
• Protein Refseq: NP_002205
• MIM: 604160
• UniProt ID: P26012
• Chromosome Location: 7p15.3
• Pathway: Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; ECM-receptor interaction, organism-specific biosystem
• Function: binding; receptor activity