Recombinant Human ITGB1 Protein, His-tagged

• Cat.No.: ITGB1-152H
• Product Overview: Recombinant Human integrin subunit beta 1(ITGB1) protein, transcript variant 1E(NM_133376), with a His tag, was expressed in human cells.

Specification

• Species: Human
• Source: Human Cells
• Tag: His
• Description: Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.185, without any preservatives.
• Molecular Mass: 86.1 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) [ Homo sapiens ]
• Official Symbol: ITGB1
• Synonyms: ITGB1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); FNRB, MDF2, MSK12; integrin beta-1; CD29; GPIIA; integrin VLA-4 beta subunit; very late activation protein, beta polypeptide; FNRB; MDF2; VLAB; MSK12; VLA-BETA
• Gene ID: 3688
• mRNA Refseq: NM_002211
• Protein Refseq: NP_002202
• MIM: 135630
• UniProt ID: P05556