Recombinant Human ITGA2 protein, His & S-tagged

• Cat.No.: ITGA2-5836H
• Product Overview: Recombinant Human ITGA2 aa. (Pro170~Ile361 (Accession # P17301)) fused with N-terminal His & S tag was produced in E. coli cells.

Specification

• Description: This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His&S
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 26.8kDa
• Protein length: Pro170~Ile361
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.7.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: ITGA2 integrin subunit alpha 2 [ Homo sapiens (human) ]
• Official Symbol: ITGA2
• Synonyms: BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2; CD49 antigen-like family member B; alpha 2 subunit of VLA-2 receptor; collagen receptor; human platelet alloantigen system 5; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; integrin alpha-2
• Gene ID: 3673
• mRNA Refseq: NM_002203.3
• Protein Refseq: NP_002194.2
• UniProt ID: P17301