Recombinant Human IRF5 Protein, His-tagged

• Cat.No.: IRF5-011H
• Product Overview: Purified recombinant protein of Human interferon regulatory factor 5 (IRF5), transcript variant 2 with a C-His tag was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.
• Molecular Mass: 57.1 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 µM filtered solution of PBS, pH 7.4

Gene Information

• Gene Name: IRF5 interferon regulatory factor 5 [ Homo sapiens (human) ]
• Official Symbol: IRF5
• Synonyms: IRF5; interferon regulatory factor 5; SLEB10; interferon regulatory factor 5
• Gene ID: 3663
• mRNA Refseq: NM_032643
• Protein Refseq: NP_116032
• MIM: 607218
• UniProt ID: Q13568