Recombinant Human IREB2 Protein, GST-tagged

• Cat.No.: IREB2-5047H
• Product Overview: Human IREB2 full-length ORF ( AAH17880, 1 a.a. - 343 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: IREB2 (Iron Responsive Element Binding Protein 2) is a Protein Coding gene. Diseases associated with IREB2 include Microcytic Anemia and Hyperferritinemia-Cataract Syndrome. Among its related pathways are Validated targets of C-MYC transcriptional activation and Glucose / Energy Metabolism. GO annotations related to this gene include RNA binding and translation repressor activity. An important paralog of this gene is ACO1.
• Molecular Mass: 63.47 kDa
• AA Sequence: MDAPKAGYAFEYLIETLNDSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNILDWKTKQSNVEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDSGELGRNSGTFSSQIENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQINLEYLSRVVFEEKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKVS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: IREB2 iron-responsive element binding protein 2 [ Homo sapiens ]
• Official Symbol: IREB2
• Synonyms: IREB2; iron-responsive element binding protein 2; iron-responsive element-binding protein 2; IRP2; IRE-BP 2; iron regulatory protein 2; ACO3; IRP2AD; FLJ23381
• Gene ID: 3658
• mRNA Refseq: NM_004136
• Protein Refseq: NP_004127
• MIM: 147582
• UniProt ID: P48200