Recombinant Human interleukin 21 Protein, His&Flag tagged
Cat.No. : | IL21-047H |
Product Overview : | Recombinant human IL-21 protein (Q9HBE4) (Gln 32-Ser 162) with both His, Flag tag at the C-terminus was expressed in HEK293. |
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Species : | Human |
Source : | HEK293 |
Tag : | Flag&His |
Protein Length : | 32-162aa |
Description : | Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. |
Tag : | C-His&Flag |
Molecular Mass : | 18 kDa |
Endotoxin : | Less than 1.0 EU/μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol. |
Reconstitution : | Reconstitute at 250 μg/mL in sterile water. |
Gene Name | IL21 interleukin 21 [ Homo sapiens (human) ] |
Official Symbol | IL21 |
Synonyms | IL21; interleukin 21; interleukin-21; IL 21; Za11; interleukin-21 isoform; IL-21; |
Gene ID | 59067 |
mRNA Refseq | NM_001207006 |
Protein Refseq | NP_001193935 |
MIM | 605384 |
UniProt ID | Q9HBE4 |
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Not For Human Consumption!
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