Recombinant Human Interleukin 10

• Cat.No.: IL10-626H
• Product Overview: IL10 isexpressed in human 293 cells as a non-covalent homodimeric glycoprotein with anapparent molecular mass of 17 kDa.

Specification

• Species: Human
• Source: HEK293
• Tag: Non
• Description: IL10 isproduced in a serum-free, chemically defined media. Glycosylation contributesto stability in cell growth media and other applications. The cytokine isgreater than 95% pure.
• Molecular Mass: 17 kDa
• Purity: > 95%The protein was resolved by SDS polyacrylamide gel electrophoresis and thegel was stained with Coomassie blue.
• Endotoxin Level: Endotoxin Free <1EU/μg
• Biological Activity: 0.3 to 1.5 ng/mL ED50
• Specific Activity: The specific activity wasdetermined by the dose-dependent stimulation of the proliferationof MC/9 cells (mouse master cell line) in presence of 200pg/mL IL-4.
• OfficialSymbol: IL10

Gene Information

• Gene Name: IL10interleukin 10 [ Homo sapiens ]
• Synonyms: IL10; interleukin10; CSIF; TGIF; IL-10; IL10A; MGC126450; MGC126451; cytokine synthesisinhibitory factor; T-cell growth inhibitory factor; OTTHUMP00000034567; Interleukin-10
• Gene ID: 3586
• mRNA Refseq: NM_000572
• Protein Refseq: NP_000563
• MIM: 124092
• UniProt ID: P22301
• Chromosome Location: 1q31-q32
• Pathway: Africantrypanosomiasis; Allograft rejection; Amoebiasis; Asthma; Autoimmune thyroiddisease; Chagas disease (American trypanosomiasis); Cytokine-cytokinereceptor interaction; Cytokines and Inflammatory Response; IL4-mediatedsignaling events; Intestinal immune network for IgA production; Jak-STATsignaling pathway; Leishmaniasis; Malaria; Pertussis; Regulation of nuclearSMAD2/3 signaling
• Function: growthfactor activity; cytokine activity; interleukin-10receptor binding