Recombinant Human Interleukin 1 Receptor Antagonist, His-tagged

• Cat.No.: IL1RN-51H
• Product Overview: Recombinant Human IL1Ra produced inE.Coliis single, a non-glycosylated, Polypeptide chain containing 152 amino acids fragment (26-177) and having a total molecular mass of 17 kDa with an amino-terminal his-tagged. The IL-1Ra His is purified by proprietary chromatographic techniques.

Specification

• Cat. No.: IL1RN-51H
• Description: IL-1Ra is the natural antagonist of the pro-inflammatory cytokines Interleukin-1α and Interleukin-1β. IL-1Ra is produced by a variety of cells including monocytes, macrophages, neutrophils and fibroblasts in response to the binding of various pro-inflammatory cytokines.
• Source: Escherichia Coli.
• Physical Appearance: Sterile Filtered clear solution.
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Formulation: Interleukin-1Ra His-tag protein is supplied in 1x PBS and 50% glycerol.
• Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
• Protein length: 26-177 a.a.

Gene Information

• Gene Name: IL1RN interleukin 1 receptor antagonist [ Homo sapiens ]
• Synonyms: IL1RN; interleukin 1 receptor antagonist; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1ra3; ICIL-1RA; MGC10430; IL1RN (IL1F3); OTTHUMP00000203730;type II interleukin-1 receptor antagonist; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); Interleukin-1 receptor antagonist protein; IL-1RN; IL1 inhibitor; Anakinra;INN; IL-1ra
• Gene ID: 3557
• mRNA Refseq: NM_000577
• Protein Refseq: NP_000568
• MIM: 147679
• UniProt ID: P18510
• Chromosome Location: 2q14.2
• Function: cytokine activity; interleukin-1 receptor antagonist activity; protein binding