Active Recombinant Equine IL1RN

• Cat.No.: IL1RN-945E
• Product Overview: Recombinant Equine IL1RN (Accession # O18999.1) His26-Gln177, fused with an N-terminal Met, was produced in E. coli.

Specification

• Source: E. coli
• Species: Equine
• Predicted N Terminal: Met
• Form: Lyophilized from a 0.2 µm filtered solution in PBS and DTT with BSA as a carrier protein.
• Bio-activity: Measured by its ability to inhibit IL-1 alpha -dependent proliferation in D10.G4.1 mouse helper T cells. Symons, J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 272.The ED50 for this effect is typically 0.75 - 3.0 µg/mL in the presence of 50 pg/mL of rhIL-1 alpha.
• Molecular Mass: Recombinant Equine IL1RN, Met-tagged has a calculated MW of 17.5 kDa.
• Protein length: His26-Gln177
• Purity: >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: IL18 interleukin 18 (interferon-gamma-inducing factor) [ Sus scrofa (pig) ]
• Official Symbol: IL18
• Synonyms: IL-18; interleukin-18; interleukin-18; IFN-gamma-inducing factor; IL-1 gamma; interferon gamma-inducing factor; interferon-gamma-inducing factor; interleukin-1 gamma
• Gene ID: 397057
• mRNA Refseq: NM_213997.1
• Protein Refseq: NP_999162.1
• UniProt ID: O19073
• Chromosome Location: chromosome: 9