Recombinant Human interferon, lambda 2, His-tagged

Description :	IFNL2, also known as Interleukin 28A (IL28A), is a cytokine distantly related to type I interferons and the IL-10 family. Interleukin 28A (IL28A), Interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). Recombinant human IFNL2 protein, fused to His-tag at N-terminus, was expressed in E.coli .
Source :	E.coli
Species :	Human
Tag :	His-tag
Form :	Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
Molecular Mass :	22.1 kDa (198aa)
AA Sequence :	MGSSHHHHHH SSGLVPRGSH MGSVPVARLH GALPDARGCH IAQFKSLSPQ ELQAFKRAKD ALEESLLLKD CRCHSRLFPR TWDLRQLQVR ERPMALEAEL ALTLKVLEAT ADTDPALVDV LDQPLHTLHH ILSQFRACIQ PQPTAGPRTR GRLHHWLYRL QEAPKKESPG CLEASVTFNL FRLLTRDLNC VASGDLCV
Purity :	>85 % by SDS - PAGE
Storage :	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration :	0.5 mg/ml (determined by Bradford assay)
Protein length :	26-200 a.a.

Gene Name	IFNL2?interferon, lambda 2 [?Homo sapiens?(human) ]
Official Symbol	IFNL2
Synonyms	IFNL2; IL28A; IL-28A; interferon, lambda 2; interferon lambda-2; IFN-lambda-2; interleukin-28A; cytokine Zcyto20; interferon lambda 2; interferon-lambda 2; interleukin 28A (interferon, lambda 2)
Gene ID	282616
mRNA Refseq	NM_172138
Protein Refseq	NP_742150
MIM	607401
UniProt ID	Q8IZJ0
Chromosome Location	19q13.13
Pathway	Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Type III interferon signaling
Function	cytokine activity