Recombinant Human Insulin Receptor-related Receptor, GST-tagged, Active
Cat.No. : | INSRR-334H |
Product Overview : | Recombinant human IRR (945-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 65 kDa. |
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Species : | Human |
Source : | Sf9 Cells |
Tag : | GST |
Protein Length : | 945-end a.a. |
Description : | IRR or insulin receptor-related receptor is a tyrosine protein kinase that is required for the appearance of male gonads and thus for male sexual differentiation. The expression of IRR mRNA is restricted to a few tissue types and has been detected in neuronal tissues as well as in neuroblastomas. As a result of its occurrence in neuroblastomas, it has speculated that IRR may be involved in tumor genesis. RT-PCR and solution hybridization/RNAse protection assay have shown strong coupling of IRR mRNA in 18 tumor cell lines. |
Sequence : | 945-end. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name | INSRR insulin receptor-related receptor [ Homo sapiens ] |
Synonyms | INSRR; insulin receptor-related receptor; IRR; IR-related receptor; EC 2.7.10.1; Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain; OTTHUMP00000038715 |
Gene ID | 3645 |
mRNA Refseq | NM_014215 |
Protein Refseq | NP_055030 |
MIM | 147671 |
UniProt ID | P14616 |
Chromosome Location | 1q21-q23 |
Pathway | Prostate cancer; Regulation of actin cytoskeleton |
Function | ATP binding; manganese ion binding; metal ion binding; nucleotide binding; protein binding; receptor activity; transferase activity; transmembrane receptor protein tyrosine kinase activity |
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Not For Human Consumption!
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