INSRR
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Official Full Name
insulin receptor-related receptor -
Overview
Insulin receptor-related protein is a protein that in humans is encoded by the INSRR gene. -
Synonyms
INSRR;insulin receptor-related receptor;insulin receptor-related protein;IRR;IR-related receptor
Recombinant Proteins
- Human
- Mouse
- Rat
- Guinea pig
- E.coli
- Insect Cells
- Mammalian Cells
- Sf9 Cells
- HEK293
- Wheat Germ
- His&T7
- GST
- Non
- His
- Flag
- Avi&Fc&His
- DDK&Myc
Involved Pathway
INSRR involved in several pathways and played different roles in them. We selected most pathways INSRR participated on our site, such as Regulation of actin cytoskeleton,Prostate cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with INSRR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Actin Cytoskeleton | FGF1,RDX,GSNB,PPP1R12A,SSH3,MYH9,FGF6A,PIP5K1C,FGF22,PAK2B |
| Prostate Cancer | INS1,HSP90AB1,CASP9,ACTL6B,CCNE1,NDRG1,PDGFRB,SMARCD1,LEF1,HSP90B1 |
Protein Function
INSRR has several biochemical functions, for example, ATP binding,insulin receptor substrate binding,phosphatidylinositol 3-kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INSRR itself. We selected most functions INSRR had, and list some proteins which have the same functions with INSRR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | CHD2,CDK18,ABCA4A,DARS2,BCS1L,BMP2K,TTLL5,ACTA1A,MAT1A,CTPS1A |
| phosphatidylinositol 3-kinase binding | JAK2,DAB1,INSRA,CALM1,PDGFRB,IGF1RA,IRS4,LCK,TYRO3,BECN1 |
| transmembrane receptor protein tyrosine kinase activity | ERBB4A,EGFRA,KITA,EK1,KITB,PDGFRA,RET,EPHB4,FLT3,ROR2 |
| insulin receptor substrate binding | PIK3CB,PRKCD,GRB2,INSRB,IGF1RB,PIK3R1,IGF1RA,INSRA,IGF1R,INSR |
Interacting Protein
INSRR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INSRR here. Most of them are supplied by our site. Hope this information will be useful for your research of INSRR.
HSP90AB1
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References
- Huijbers, MG; Zhang, W; et al. MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:20783-20788(2013).
- Zhou, T; He, X; et al. Implication of dysregulation of the canonical wingless-type MMTV integration site (WNT) pathway in diabetic nephropathy. DIABETOLOGIA 55:255-266(2012).
