Recombinant Human inhibitor of growth family, member 2, His-tagged

• Cat.No.: ING2-308H
• Product Overview: ING2, 1-280aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-280 a.a.
• Description: The ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. Recombinant human ING2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 35.2kDa (303aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMLGQQQQ QLYSSAALLT GERSRLLTCY VQDYLECVES LPHDMQRNVS VLRELDNKYQ ETLKEIDDVY EKYKKEDDLN QKKRLQQLLQ RALINSQELG DEKIQIVTQM LELVENRARQ MELHSQCFQD PAESERASDK AKMDSSQPER SSRRPRRQRT SESRDLCHMA NGIEDCDDQP PKEKKSKSAK KKKRSKAKQE REASPVEFAI DPNEPTYCLC NQVSYGEMIG CDNEQCPIEW FHFSCVSLTY KPKGKWYCPK CRGDNEKTMD KSTEKTKKDR RSR
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ING2 inhibitor of growth family, member 2 [ Homo sapiens ]
• Official Symbol: ING2
• Synonyms: ING2; inhibitor of growth family, member 2; ING1L, inhibitor of growth family, member 1 like; inhibitor of growth protein 2; p33ING2; p32; ING1Lp; inhibitor of growth 1-like protein; ING1L
• Gene ID: 3622
• mRNA Refseq: NM_001564
• Protein Refseq: NP_001555
• MIM: 604215
• UniProt ID: Q9H160
• Chromosome Location: 4q35.1
• Pathway: Senescence and Autophagy, organism-specific biosystem
• Function: DNA binding; chromatin binding; metal ion binding; methylated histone residue binding; phosphatidylinositol binding; protein binding; protein complex binding; zinc ion binding