Recombinant Human IL33 Protein

• Cat.No.: IL33-166H
• Product Overview: Recombinant Human IL-33 is produced by our E.coli expression system and the target gene encoding Ser112-Thr270 is expressed.

Specification

• Species: Human
• Source: E.coli
• Protein Length: 112-270 a.a.
• Description: Interleukin 33 (IL-33) is a cytokine that belongs to the IL-1 superfamily. IL-33 is expressed at high level in high endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes. As a type 2 cytokines, IL-33 plays a central role in helminthic infection and allergic disorders by amplifying immune responses during tissue injury. Studies also suggested that IL-33 might act as an intracellular nuclear factor besides the function of cytokine.
• Form: Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
• Molecular Mass: Predicted Molecular Weight: 17.9kDa
  Apparent Molecular Weight: 18.4-25kDa, reducing conditions.
• AA Sequence: Ser112-Thr270
• Endotoxin: Less than 1 EU/ug.
• Purity: >95%
• Storage: Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
  Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
• Reconstitution: It is not recommended to reconstitute to a concentration less than 100μg/ml.
  Dissolve the lyophilized protein in distilled water.
  Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Quality Statement: Purity: greater than 95% as determined by reducing SDS-PAGE.
• Shipping: The product is shipped at ambient temperature.
  Upon receipt, store it immediately at the temperature listed below.

Gene Information

• Gene Name: IL33 interleukin 33 [ Homo sapiens (human) ]
• Official Symbol: IL33
• Synonyms: Interleukin-33; IL-33; Interleukin-1 Family Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV; DVS27; IL1F11; NFEHEV
• Gene ID: 90865
• mRNA Refseq: NM_001199640.2
• Protein Refseq: NP_001186569.1
• MIM: 608678
• UniProt ID: O95760