Recombinant Human IL26 Protein (22-171 aa), His-B2M-tagged

• Cat.No.: IL26-2446H
• Product Overview: Recombinant Human IL26 Protein (22-171 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-B2M tag at the N-terminal. Protein Description: Full Length of Mature Protein.

Specification

• Description: May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
• Source: E. coli
• Species: Human
• Tag: His&B2M
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 31.6 kDa
• Protein length: 22-171 aa
• AA Sequence: KHKQSSFTKSCYPRGTLSQAVDALYIKAAWLKATIPEDRIKNIRLLKKKTKKQFMKNCQFQEQLLSFFMEDVFGQLQLQGCKKIRFVEDFHSLRQKLSHCISCASSAREMKSITRMKRIFYRIGNKGIYKAISELDILLSWIKKLLESSQ
• Purity: > 85% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: IL26 interleukin 26 [ Homo sapiens ]
• Official Symbol: IL26
• Synonyms: IL26; interleukin 26; interleukin-26; AK155; IL 26; IL-26
• Gene ID: 55801
• mRNA Refseq: NM_018402
• Protein Refseq: NP_060872
• MIM: 605679
• UniProt ID: Q9NPH9