Recombinant Human IL17A protein, His & T7-tagged
Cat.No. : | IL17A-870H |
Product Overview : | Recombinant Human IL17A aa. (Ile20~Ala155 (Accession # Q16552)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
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Species : | Human |
Source : | E.coli |
Tag : | His&T7 |
Protein Length : | Ile20~Ala155 |
Description : | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 19.4kDa |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Characteristic : | The isoelectric point is 9. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4 |
Gene Name | IL17A interleukin 17A [ Homo sapiens (human) ] |
Official Symbol | IL17A |
Synonyms | IL17A; interleukin 17A; IL17; CTLA8; IL-17; CTLA-8; IL-17A; interleukin-17A; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) |
Gene ID | 3605 |
mRNA Refseq | NM_002190.2 |
Protein Refseq | NP_002181.1 |
UniProt ID | Q16552 |
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Not For Human Consumption!
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