Recombinant Human IL17A protein, His & T7-tagged

Cat.No. : IL17A-870H
Product Overview : Recombinant Human IL17A aa. (Ile20~Ala155 (Accession # Q16552)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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Species : Human
Source : E.coli
Tag : His&T7
Protein Length : Ile20~Ala155
Description : The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 19.4kDa
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Characteristic : The isoelectric point is 9.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4
Gene Name IL17A interleukin 17A [ Homo sapiens (human) ]
Official Symbol IL17A
Synonyms IL17A; interleukin 17A; IL17; CTLA8; IL-17; CTLA-8; IL-17A; interleukin-17A; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Gene ID 3605
mRNA Refseq NM_002190.2
Protein Refseq NP_002181.1
UniProt ID Q16552

Not For Human Consumption!

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