Recombinant Human IGFBP7, His-tagged
Cat.No. : | IGFBP7-1630H |
Product Overview : | Recombinant Human Human IGFBP-rp1 (Asp 30 -Leu 282) encoding the signal peptide from human CD33 (Met 1 - Ala 16) was fused to the N-terminal 10X his tagged mature human IGFBP-rp1 (Asp 30 - Leu 282) and inserted into a suitable expression vector. The recombinant protein was expressed in a mouse myeloma cell line,NSO. |
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Species : | Human |
Source : | Mammalian Cells |
Tag : | His |
Protein Length : | 30-282;1-16 a.a. |
Description : | Insulin-like growth factor binding protein 7, also known as IGFBP7 is a secretory protein. It is abundantly expressed in the uterine endometrium during the secretory phase of the menstrual cycle. Decreased IGFBP7 expression has been observed in some cancers and leiomyomata.IGFBP7 plays a potential tumor suppressor role in colorectal carcinogenesis. |
State Of Matter : | Lyophilized. |
Purity : | >90% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Molecular Weight : | The predicted molecular weight of Recombinant Human IGF-BP7 is Mr 27.5 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 36 kDa. |
Formulation : | This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives present. |
Biological Activity : | The biological activity of Human IGF-BP7 was determined by by its ability to bind rh6Ckine/CCL21. Immobilized rhIGFBP-rp1 at 1 μg/mL (100 μL/well) can bind rh6Ckine/CCL21 with a linear range of 0.08 - 5 ng/mL in a functional ELISA. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Gene Name | IGFBP7 insulin-like growth factor binding protein 7 [ Homo sapiens ] |
Synonyms | insulin-like growth factor binding protein 7; PSF; FSTL2; MAC25; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP7; IBP-7; IGFBP-rP1; TAF; IGF-binding protein 7; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor |
Gene ID | 3490 |
mRNA Refseq | NM_001553 |
Protein Refseq | NP_001544 |
MIM | 602867 |
UniProt ID | Q16270 |
Chromosome Location | 4q12 |
Function | insulin-like growth factor binding |
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IGFBP7-303H | Recombinant Human IGFBP7 Protein, His-tagged | +Inquiry |
Igfbp7-3490M | Recombinant Mouse Igfbp7 Protein, Myc/DDK-tagged | +Inquiry |
IGFBP7-2949H | Recombinant Human IGFBP7 Protein (Gly130-Ala280), N-His tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
IGFBP7-1694HCL | Recombinant Human IGFBP7 cell lysate | +Inquiry |
Not For Human Consumption!
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