Recombinant Human IGFALS, GST-tagged

• Cat.No.: IGFALS-14104H
• Product Overview: Recombinant Human IGFALS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-344a.a.
• Description: The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: IGFALS insulin-like growth factor binding protein, acid labile subunit [ Homo sapiens ]
• Official Symbol: IGFALS
• Synonyms: IGFALS; insulin-like growth factor binding protein, acid labile subunit; insulin-like growth factor-binding protein complex acid labile subunit; ALS; insulin-like growth factor binding protein complex acid labile chain
• Gene ID: 3483
• mRNA Refseq: NM_001146006
• Protein Refseq: NP_001139478
• UniProt ID: P35858
• Chromosome Location: 16p13.3
• Pathway: Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs), organism-specific biosystem
• Function: insulin-like growth factor binding