Recombinant Human IFT122, His-tagged

• Cat.No.: IFT122-14088H
• Product Overview: Recombinant Human IFT122 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-359a.a.
• Description: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: IFT122 intraflagellar transport 122 homolog (Chlamydomonas) [ Homo sapiens ]
• Official Symbol: IFT122
• Synonyms: IFT122; intraflagellar transport 122 homolog (Chlamydomonas); WD repeat domain 10 , WDR10; intraflagellar transport protein 122 homolog; SPG; WDR10p; WDR140; WD repeat domain 10; WD repeat-containing protein 10; WD repeat-containing protein 140; CED; WDR10
• Gene ID: 55764
• mRNA Refseq: NM_018262
• Protein Refseq: NP_060732
• MIM: 606045
• UniProt ID: Q9HBG6
• Chromosome Location: 3q21