Recombinant Human IFNL3, His-tagged

• Cat.No.: IFNL3-60H
• Product Overview: Recombinant human IFNL3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Description: IFNL3, also known as Interferon lambda-3, is a secreted protein which belongs to the IL-28/IL-29 family. It is a cytokine with immunomodulatory activity. It up-regulates MHC class I antigen expression. This protein displays potent antiviral activity and antitumor activity. It seems to signal through the Jak-STAT pathway. It also contributes to viral resistance and is known to be upregulated by interferons and by RNA virus infection.
• Form: Liquid. In phosphate buffered saline (pH 7.4) containing 20% glycerol, 1mM EDTA, 0.1mM PMSF.
• Molecular Mass: 20.4kDa (181aa) 18-28kDa (SDS-PAGE under reducing conditions.)
• AA Sequence: VPVARLRGAL PDARGCHIAQ FKSLSPQELQ AFKRAKDALE ESLLLKDCKC RSRLFPRTWD LRQLQVRERP VALEAELALT LKVLEATADT DPALGDVLDQ PLHTLHHILS QLRACIQPQP TAGPRTRGRL HHWLHRLQEA PKKESPGCLE ASVTFNLFRL LTRDLNCVAS GDLCVHHHHH H
• Endotoxin: < 1.0 eu per 1 microgram of protein (determined by lal
• Purity: >85% by SDS - PAGE.
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by Bradford assay)