Recombinant Human IFNAR2, GST-tagged
| Cat.No. : | IFNAR2-14078H |
| Product Overview : | Recombinant Human IFNAR2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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| Description : | The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. |
| Source : | E.coli |
| Species : | Human |
| Tag : | GST |
| Protein length : | 230-331a.a. |
| Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
| Gene Name | IFNAR2 interferon (alpha, beta and omega) receptor 2 [ Homo sapiens ] |
| Official Symbol | IFNAR2 |
| Synonyms | IFNAR2; interferon (alpha, beta and omega) receptor 2; IFNABR; interferon alpha/beta receptor 2; IFN-R-2; IFN-alpha binding protein; IFN-alpha/beta receptor 2; type I interferon receptor 2; interferon alpha binding protein; human interferon alpha/beta receptor; interferon-alpha/beta receptor beta chain; IFN-R; IFNARB; IFN-alpha-REC; |
| Gene ID | 3455 |
| mRNA Refseq | NM_000874 |
| Protein Refseq | NP_000865 |
| MIM | 602376 |
| UniProt ID | P48551 |
| Chromosome Location | 21q22.1 |
| Pathway | Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Herpes simplex infection, organism-specific biosystem; |
| Function | protein binding; protein kinase binding; receptor activity; type I interferon binding; type I interferon receptor activity; |
Not For Human Consumption!
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