Recombinant Human ID2

• Cat.No.: ID2-28380TH
• Product Overview: Recombinant full length Human ID2 protein with a proprietary tag; predicted molecular weight 40.48 kDa, inclusive of tag. AAH30639

Specification

• Species: Human
• Source: Wheat Germ
• Tag: Non
• Protein Length: 135 amino acids
• Description: The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3.
• Molecular Weight: 40.480kDa inclusive of tags
• Tissue specificity: Highly expressed in early fetal tissues, including those of the central nervous system.
• Biological activity: useful for Antibody Production and Protein Array
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Contains 1 basic helix-loop-helix (bHLH) domain.

Gene Information

• Gene Name: ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein [ Homo sapiens ]
• Official Symbol: ID2
• Synonyms: ID2; inhibitor of DNA binding 2, dominant negative helix-loop-helix protein; DNA-binding protein inhibitor ID-2; bHLHb26; cell growth inhibiting gene 8; GIG8
• Gene ID: 3398
• mRNA Refseq: NM_002166
• Protein Refseq: NP_002157
• MIM: 600386
• Uniprot ID: Q02363
• Chromosome Location: 2p25
• Pathway: HIF-1-alpha transcription factor network, organism-specific biosystem; Id Signaling Pathway, organism-specific biosystem; Regulation of Wnt-mediated beta catenin signaling and target gene transcription, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem
• Function: protein binding