Recombinant Human ICAM5 protein, His & GST-tagged

• Cat.No.: ICAM5-588H
• Product Overview: Recombinant Human ICAM5 aa. (Arg409~Pro674 (Accession # Q9UMF0)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 60.0kDa
• Protein length: Arg409~Pro674
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.7.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4

Gene Information

• Gene Name: ICAM5 intercellular adhesion molecule 5 [ Homo sapiens (human) ]
• Official Symbol: ICAM5
• Synonyms: ICAM5; intercellular adhesion molecule 5; TLN; TLCN; intercellular adhesion molecule 5; ICAM-5; intercellular adhesion molecule 5, telencephalin; telencephalin
• Gene ID: 7087
• mRNA Refseq: NM_003259.3
• Protein Refseq: NP_003250.3
• UniProt ID: Q9UMF0