Recombinant Human HOXD4, His-tagged

• Cat.No.: HOXD4-13914H
• Product Overview: Recombinant Human HOXD4 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-255a.a.
• Description: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5 end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: HOXD4 homeobox D4 [ Homo sapiens ]
• Official Symbol: HOXD4
• Synonyms: HOXD4; homeobox D4; homeo box D4 , HOX4, HOX4B; homeobox protein Hox-D4; homeobox protein Hox-4B; homeobox protein HHO.C13; homeobox protein Hox-5.1; Hox-4.2, mouse, homolog of homeo box X; HOX4; HOX4B; HHO.C13; HOX-5.1; Hox-4.2
• Gene ID: 3233
• mRNA Refseq: NM_014621
• Protein Refseq: NP_055436
• UniProt ID: P09016
• Chromosome Location: 2q31.1
• Function: sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity