Recombinant Human HOXB8 Protein, GST-tagged

• Cat.No.: HOXB8-4968H
• Product Overview: Human HOXB8 full-length ORF (BAC04730.1, 1 a.a. - 243 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. [provided by RefSeq
• Molecular Mass: 54.1 kDa
• AA Sequence: MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAVACHGDPDNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFHSSKCEQEELEKQKLERAPEAADEGDAQKGDKK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HOXB8 homeobox B8 [ Homo sapiens ]
• Official Symbol: HOXB8
• Synonyms: HOXB8; homeobox B8; homeo box B8 , HOX2, HOX2D; homeobox protein Hox-B8; homeo box 2D; homeo box B8; homeobox protein Hox-2D; homeobox protein Hox-2.4; HOX2; HOX2D; Hox-2.4
• Gene ID: 3218
• mRNA Refseq: NM_024016
• Protein Refseq: NP_076921
• MIM: 142963
• UniProt ID: P17481