HOXB8
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Official Full Name
homeobox B8 -
Overview
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. -
Synonyms
HOXB8;homeobox B8;homeo box B8 , HOX2, HOX2D;homeobox protein Hox-B8;Homeobox protein Hox B8;Homeobox protein HoxB8;HOX 2;Hox 2.4;HOX 2D;HOX B8;HOX2;Hox2.4;HOX2D;homeo box 2D;homeo box B8;OTTHUMP00000216943;homeobox protein Hox-2D;homeobox protein Hox-2.4;Hox-2.4
Recombinant Proteins
- Rhesus macaque
- Human
- Chicken
- Mammalian Cell
- Wheat Germ
- HEK293
- E.coli
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HOXB8-2132R | Recombinant Rhesus monkey HOXB8 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| HOXB8-4968H | Recombinant Human HOXB8 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HOXB8-6473C | Recombinant Chicken HOXB8 | Mammalian Cell | Chicken | His |
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| HOXB8-5420HCL | Recombinant Human HOXB8 293 Cell Lysate | HEK293 | Human | Non |
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| HOXB8-1894H | Recombinant Human HOXB8 Protein, His-tagged | E.coli | Human | His |
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| HOXB8-1953R | Recombinant Rhesus Macaque HOXB8 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| HOXB8-1953R-B | Recombinant Rhesus Macaque HOXB8 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| HOXB8-3721HF | Recombinant Full Length Human HOXB8 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 243 amino acids |
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Involved Pathway
HOXB8 involved in several pathways and played different roles in them. We selected most pathways HOXB8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXB8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
HOXB8 has several biochemical functions, for example, sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXB8 itself. We selected most functions HOXB8 had, and list some proteins which have the same functions with HOXB8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | IRF4A,KAT7B,FOXJ1A,RUNX1T1,SCAND3,MZF1,FEV,CLOCKA,ZNF711,ZNF146 |
| sequence-specific DNA binding | VRTN,HOXA5A,FOXN2,PRDM16,GLI1,CREBZF,USF1,POU3F2A,FOXG1B,ATF7A |
Interacting Protein
HOXB8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXB8 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXB8.
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