Recombinant Human Homer Homolog 1, His-tagged

• Cat.No.: HOMER1-5027H
• Product Overview: Recombinant Homer 1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: Homer 1 (Homer protein homolog 1) belongs to Homer family of proteins that regulate signal transduction through, and the trafficking of glutamate receptors as well as maintain and regulate extracellular glutamate levels in corticolimbic brain regions. The Homer 1 is enriched at excitatory synapses and binds group 1 metabotropic glutamate receptors (mGluRs).
• Concentration: 1 mg/ml
• Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 0.1M NaCl, 20% glycerol, and 1mM DTT.
• Purity: > 90% by SDS - PAGE
• Sequence: 1-354 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMGE QPIFSTRAHV FQIDPNTKKN WVPTSKHAVT VSYFYDSTRN VYRIISLDGS KAIINSTITP NMTFTKTSQK FGQWADSRAN TVYGLGFSSE HHLSKFAEKF QEFKEAARLA KEKSQEKMEL TSTPSQESAG GDLQSPLTPE SINGTDDERT PDVTQNSEPR AEPTQNALPF SHSSA
• Molecular Mass: 44.5 kDa (391 aa), confirmed by MALDI-TOF.
• Applications: SDS-PAGE
• Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: HOMER1 homer homolog 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: HOMER1
• Synonyms: HOMER1; homer homolog 1 (Drosophila); HOMER; SYN47; Ves-1; HOMER1A; HOMER1B; HOMER-1B; HOMER1C; HOMER1; Homer protein homolog 1; homer 1; OTTHUMP00000165782; homer, neuronal immediate early gene, 1
• Gene ID: 9456
• mRNA Refseq: NM_004272
• Protein Refseq: NP_004263
• MIM: 604798
• UniProt ID: Q86YM7
• Chromosome Location: 5q14.2
• Pathway: Glutamatergic synapse
• Function: protein binding