HOMER1
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Official Full Name
homer homolog 1 -
Overview
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. -
Synonyms
HOMER1;homer homolog 1 (Drosophila);homer protein homolog 1;HOMER 1B;SYN47;Ves 1;homer-1;homer, neuronal immediate early gene, 1;HOMER;Ves-1;HOMER1A;HOMER1B;HOMER1C;homer homolog 1
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cells
- Wheat Germ
- Human
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Avi
- Fc
Involved Pathway
HOMER1 involved in several pathways and played different roles in them. We selected most pathways HOMER1 participated on our site, such as FoxO signaling pathway,Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with HOMER1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glutamatergic synapse | GNG13,GRM6,PPP3CB,GRM3,GNAI2,SHANK3,PLD1,PLD2,SLC1A2,GRM5 |
| FoxO signaling pathway | FOXO3B,SMAD4,FOXO3,MAPK1,GADD45G,SLC2A4,RAF1B,GADD45AA,PRKAG3B,AKT1 |
Protein Function
HOMER1 has several biochemical functions, for example, G-protein coupled glutamate receptor binding,identical protein binding,ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOMER1 itself. We selected most functions HOMER1 had, and list some proteins which have the same functions with HOMER1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | VIL1,DYNLT1C,AGXT2L2,SERPINA1A,NUP153,CORO1B,SNCA,Serpina1b,FAS,WAS |
| protein complex scaffold | ISCU,WWC1,MAGI1B,CHCHD3,MPP7,CNOT1,SLC9A3R2,CAPN3,AKAP13,WWC3 |
| protein heterodimerization activity | VAPB,HIST1H2AI,GTF2A2,HIST1H2BK,NPAS4,CYBA,GABPA,MCL1A,UGT1A7,DDIT3 |
| type 5 metabotropic glutamate receptor binding | DNM3,ADORA2A |
| G-protein coupled glutamate receptor binding | HOMER2,HOMER1B,HOMER3 |
| scaffold protein binding | DSP,NLGN4Y,SHANK1,NOS1,KRT5,CRIPT,PARK7,NLRP1,KCNQ1,ATP2B4 |
| ion channel binding | TRPC1,PHPT1,KCNB1,RYR2,AKAP9,KCNQ3,CDH5,ASPH,YWHAE,ABCC9 |
| protein binding | CTR9,GLRB,KRTAP5-6,KIR2DL1,C6,MAPK4,LRRC7,PLSCR3,NR2E3,ZCCHC11 |
| signaling adaptor activity | SH2B3,LDLRAP1,GNB2L1,SH2B2,SH2B1,MPP7,AFAP1L2 |
Interacting Protein
HOMER1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOMER1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOMER1.
SARG;HOMER3;C19orf57;Snw1;FAT1;Cdc16;C1orf116;ABI3;DBN1;Cep44
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