Recombinant Human HMOX1

• Cat.No.: HMOX1-27002TH
• Product Overview: Recombinant full length Human Heme Oxygenase 1 , MWt 32kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 288 amino acids
• Description: Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
• Molecular Weight: 32.000kDa
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 7.50Constituents:0.79% Tris HCl, 2% Glycerol, 0.02% DTT, 2.63% Sodium chloride, 0.002% PMSF
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the heme oxygenase family.

Gene Information

• Gene Name: HMOX1 heme oxygenase (decycling) 1 [ Homo sapiens ]
• Official Symbol: HMOX1
• Synonyms: HMOX1; heme oxygenase (decycling) 1; heme oxygenase 1; bK286B10; HO 1
• Gene ID: 3162
• mRNA Refseq: NM_002133
• Protein Refseq: NP_002124
• MIM: 141250
• Uniprot ID: P09601
• Chromosome Location: 22q12
• Pathway: HIF-1-alpha transcription factor network, organism-specific biosystem; Heme degradation, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Keap1-Nrf2 Pathway, organism-specific biosystem; Metabolism, organism-specific biosystem
• Function: enzyme binding; heme binding; heme oxygenase (decyclizing) activity; heme oxygenase (decyclizing) activity; metal ion binding