Recombinant Human Histone Deacetylase 6, FLAG-tagged
Cat.No. : | HDAC6-398H |
Product Overview : | Recombinanthuman HDAC6 was expressed in E. coli as the full length protein with anN-terminal FLAG tag. The molecular weight of the protein is 132 kDa. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | E.coli |
Tag : | Flag |
Description : | HDAC6is a histone deacetylase containig two HDAC catalytic domains. HDAC6 is anenzyme that in humans is encoded by the HDAC6 gene. Histones play a critical rolein transcriptional regulation, cell cycle progression, and developmentalevents. It contains an internal duplication of two catalytic domains whichappear to function independently of each other. |
Reconstitution : | 20 mM Tris-HCl (pH7.3), 300 mM KCl, 0.2 mM EDTA and 20%glycerol. |
Contents : | 10g recombinant HDAC6 protein, 0.5 g/l. |
Dilution of Protein : | RecombinantHDAC6 is supplied in solution and should be kept as a solution in ordertomaintain full activity. |
Application : | RecombinantHDAC6 is suitable for use in histone deacetylase assays. Arecommendedstarting point for the HDAC assay is 20-100 ng of recombinant proteinperreaction. |
Storage : | Recombinantproteins in solution are temperature sensitive and should be stored at-80°Cto prevent degradation. Avoid repeated freeze/thaw cycles and keep on icewhennot in storage. |
Full Length : | Full L. |
Gene Name | HDAC6 histonedeacetylase 6 [ Homo sapiens ] |
Official Symbol | HDAC6 |
Synonyms | HDAC6;histone deacetylase 6; HD6; JM21; FLJ16239; EC 3.5.1.98; KIAA0901;OTTHUMP00000032398; OTTHUMP00000197663 |
Gene ID | 10013 |
mRNA Refseq | NM_006044 |
Protein Refseq | NP_006035 |
MIM | 300272 |
UniProt ID | Q9UBN7 |
Chromosome Location | Xp11.23 |
Pathway | Cell cycle; NOTCH1 Intracellular DomainRegulates Transcription; Signal Transduction; Signaling by NOTCH; Signalingby NOTCH1; Signaling events mediated by HDAC Class I; Signaling eventsmediated by HDAC Class II; TNF-alpha/NF-kB Signaling Pathway |
Function | Hsp90 protein binding; NAD-dependenthistone deacetylase activity (H3-K14 specific); NAD-dependent histonedeacetylase activity (H3-K9 specific); NAD-dependent histone deacetylaseactivity (H4-K16 specific); actin binding; alpha-tubulin binding;beta-catenin binding; beta-tubulin binding; dynein complex binding; enzymebinding; histone deacetylase activity; histone deacetylase activity (H3-K16specific); histone deacetylase binding; hydrolase activity; metal ion binding |
◆ Recombinant Proteins | ||
HDAC6-28922TH | Recombinant Human HDAC6 | +Inquiry |
HDAC6-1359H | Active Recombinant Human HDAC6, GST-tagged | +Inquiry |
HDAC6-3026H | Recombinant Human HDAC6 protein, His-tagged | +Inquiry |
HDAC6-2236H | Recombinant Human HDAC6 Protein, His-tagged | +Inquiry |
Hdac6-1371R | Recombinant Rat Hdac6 protein, His & T7-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
HDAC6-5603HCL | Recombinant Human HDAC6 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All HDAC6 Products
Required fields are marked with *
My Review for All HDAC6 Products
Required fields are marked with *
0
Inquiry Basket