Recombinant Human HES6, His-tagged

• Cat.No.: HES6-13748H
• Product Overview: Recombinant Human HES6 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-224a.a.
• Description: This gene encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of this gene family regulate cell differentiation in numerous cell types. The protein encoded by this gene functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: HES6 hairy and enhancer of split 6 (Drosophila) [ Homo sapiens ]
• Official Symbol: HES6
• Synonyms: HES6; hairy and enhancer of split 6 (Drosophila); transcription cofactor HES-6; bHLHb41; C-HAIRY1; class B basic helix-loop-helix protein 41; HES-6; bHLHc23
• Gene ID: 55502
• mRNA Refseq: NM_001142853
• Protein Refseq: NP_001136325
• MIM: 610331
• UniProt ID: Q96HZ4
• Chromosome Location: 2q37.3
• Pathway: Delta-Notch Signaling Pathway, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem
• Function: DNA binding; sequence-specific DNA binding transcription factor activity; transcription cofactor activity; transcription factor binding