Recombinant Human Heat Shock Protein 90kDa Alpha (cytosolic), Class A Member 1, His-tagged

• Cat.No.: HSP90AA1-135H
• Product Overview: Recombinant human HSP90AA1was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: HSP90AA1 has beenidentified in the cytosol, nucleus and endoplasmic reticulum, and is reportedto exist in many tissue types. In several tissues, including smooth muscle,HSP-90 comprises up to 2% of total cellular protein. HSP90 functions as adimer, assembled as part of heterocomplex. It possesses ATP-binding site andlow ATPase activity.
• Form: The protein (1mg/ml) contains 20 mM Tris-HCl, pH 7.4 + 100 mM NaCl.
• Purity: Greater than 95.0%as determined by analysis by RP-HPLC and by analysis by reducing andnon-reducing SDS-PAGE Coomassie.
• Storage: Store at 2-4°C ifentire vial will be used within 2-4 weeks. Store, frozen at -20°C for longerperiods of time. For long term storage it is recommended to add a carrierprotein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
• OfficialSymbol: HSP90AA1

Gene Information

• Gene Name: HSP90AA1 heat shock protein90kDa alpha (cytosolic), class A member 1 [ Homo sapiens ]
• Synonyms: HSP90AA1; heat shockprotein 90kDa alpha (cytosolic), class A member 1; HSPN; LAP2; HSP86;HSPC1; HSPCA; Hsp89; Hsp90; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4;FLJ31884; heat shock protein HSP 90-alpha; HSP 86; heat shock 86 kDa; OTTHUMP00000246766;OTTHUMP00000246767; heat shock 90kD protein 1, alpha; heat shock 90kDaprotein 1, alpha; renal carcinoma antigen NY-REN-38; heat shock 90kD protein,alpha-like 4; heat shock 90kD protein 1, alpha-like 4
• Gene ID: 3320
• mRNA Refseq: NM_005348
• Protein Refseq: NP_005339
• MIM: 140571
• UniProt ID: Q86SX1
• Chromosome Location: 14q32.33
• Pathway: Antigen processingand presentation; Axon guidance; Cell Cycle; Centrosome maturation; Class IPI3K signaling events; Developmental Biology; EBV LMP1 signaling; ErbBreceptor signaling network; Glucocorticoid receptor regulatory network; IL-2Signaling Pathway; Integrins in angiogenesis; Metabolism of nitric oxide;NOD-like receptor signaling pathway; Progesterone-mediated oocyte maturation
• Function: ATP binding; ATPaseactivity; TPR domain binding; identical protein binding; nitric-oxidesynthase regulator activity; nucleotide binding; protein binding; proteinhomodimerization activity; protein serine/threonine kinase activity; unfoldedprotein binding