Recombinant Human HDAC2
Cat.No. : | HDAC2-28264TH |
Product Overview : | Recombinant full length Human HDAC2 with a C-terminal proprietary tag. Expressed by baculovirus in Sf9 insect cells. Genbank Number: |
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Species : | Human |
Source : | Insect Cells |
Tag : | Non |
Protein Length : | 488 amino acids |
Description : | This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. |
Molecular Weight : | 92.000kDa inclusive of tags |
Tissue specificity : | Widely expressed; lower levels in brain and lung. |
Form : | Liquid |
Purity : | by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the histone deacetylase family. HD type 1 subfamily. |
Gene Name | HDAC2 histone deacetylase 2 [ Homo sapiens ] |
Official Symbol | HDAC2 |
Synonyms | HDAC2; histone deacetylase 2; RPD3; YAF1; |
Gene ID | 3066 |
mRNA Refseq | NM_001527 |
Protein Refseq | NP_001518 |
MIM | 605164 |
Uniprot ID | Q92769 |
Chromosome Location | 6q21 |
Pathway | Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Chronic myeloid leukemia, organism-specific biosystem; Chronic myeloid leukemia, conserved biosystem; |
Function | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); chromatin binding; enzyme binding; |
◆ Recombinant Proteins | ||
HDAC2-1590H | Recombinant Human Histone Deacetylase 2, GST-tagged | +Inquiry |
HDAC2-2986H | Recombinant Human HDAC2 Protein (386-488), His tagged | +Inquiry |
HDAC2-21R | Recombinant Rat HDAC2 protein(Met1~Pro488), His-tagged | +Inquiry |
HDAC2-393H | Active Recombinant Human HDAC2 protein, His-tagged | +Inquiry |
HDAC2-93H | Recombinant Human HDAC2 Protein, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
HDAC2-5605HCL | Recombinant Human HDAC2 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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