Recombinant Human HDAC2

Cat.No. : HDAC2-28264TH
Product Overview : Recombinant full length Human HDAC2 with a C-terminal proprietary tag. Expressed by baculovirus in Sf9 insect cells. Genbank Number:
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Species : Human
Source : Insect Cells
Tag : Non
Protein Length : 488 amino acids
Description : This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
Molecular Weight : 92.000kDa inclusive of tags
Tissue specificity : Widely expressed; lower levels in brain and lung.
Form : Liquid
Purity : by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the histone deacetylase family. HD type 1 subfamily.
Gene Name HDAC2 histone deacetylase 2 [ Homo sapiens ]
Official Symbol HDAC2
Synonyms HDAC2; histone deacetylase 2; RPD3; YAF1;
Gene ID 3066
mRNA Refseq NM_001527
Protein Refseq NP_001518
MIM 605164
Uniprot ID Q92769
Chromosome Location 6q21
Pathway Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Chronic myeloid leukemia, organism-specific biosystem; Chronic myeloid leukemia, conserved biosystem;
Function NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); chromatin binding; enzyme binding;

Not For Human Consumption!

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