Recombinant Human HAPLN1, His-tagged

• Cat.No.: HAPLN1-253H
• Product Overview: HAPLN1, 16-354 aa, Human, His tag, E.coli

Specification

• Description: : HAPLN1 belongs to the HAPLN family. It contains 1 Ig-like V-type (immunoglobulin-like) domain and contains 2 Link domains. This protein stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix. Recombinant human HAPLN1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
• Molecular Mass: 40.9kDa (362aa)
• Protein length: 16-354aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSDHLSDNY TLDHDRAIHI QAENGPHLLV EAEQAKVFSH RGGNVTLPCK FYRDPTAFGS GIHKIRIKWT KLTSDYLKEV DVFVSMGYHK KTYGGYQGRV FLKGGSDSDA SLVITDLTLE DYGRYKCEVI EGLEDDTVVV ALDLQGVVFP YFPRLGRYNL NFHEAQQACL DQDAVIASFD QLYDAWRGGL DWCNAGWLSD GSVQYPITKP REPCGGQNTV PGVRNYGFWD KDKSRYDVFC FTSNFNGRFY YLIHPTKLTY DEAVQACLND GAQIAKVGQI FAAWKILGYD RCDAGWLADG SVRYPISRPR RRCSPTEAAV RFVGFPDKKH KLYGVYCFRA YN
• Purity: >80% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: HAPLN1 hyaluronan and proteoglycan link protein 1 [ Homo sapiens ]
• Official Symbol: HAPLN1
• Synonyms: HAPLN1; hyaluronan and proteoglycan link protein 1; cartilage linking protein 1 , CRTL1; Cartilage link protein; cartilage-link protein; proteoglycan link protein; cartilage linking protein 1; cartilage-linking protein 1; CRTL1
• Gene ID: 1404
• mRNA Refseq: NM_001884
• Protein Refseq: NP_001875
• MIM: 115435
• UniProt ID: P10915
• Chromosome Location: 5q14.3
• Function: binding; hyaluronic acid binding